Dendritic cells as components of adaptive immune system in mammals

Volume 1, Issue 3, Article 5 - 2020

Authors: Lucie Kratochvílová ;Petr Sláma

Copyright © 2020 . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cells of innate immunity form a heterogeneous group of myeloid and lymphoid populations includes cells that serve as the first line of defense of the organism against pathogens - granulocytes, monocytes, macrophages. Furthermore, cells that protect against external influences or disorders of internal balance and intracellular infections - NK cells and dendritic cells (DCs). Due to their ability to respond to subtle changes in the body (e.g. during tumor transformation or the initial stage of infection). DCs and NK cells can translate this information but also receive it through receptor interactions and chemokines, lymphokines and neurotransmitters. Although the individual subpopulations of innate immune cells are somehow specialized, the ability to recognize and the cytotoxic executive function are common to all cells. In this review, we describe the functions of dendritic cells in mammals. DCs play an important role in infectious immunity and autoimmunity.

How To Cite This Article

Kratochvílová & Slama. Dendritic cells as components of adaptive immune system in mammals. Veterinary Medicine and Public Health Journal 1(3); 2020: 96-98